MMSE-2 is a new standard version that is equivalent to the original MMSE. It has 3 new brief and expanded forms.MMSE-2 retains the original’s clinical utility and efficiency while expanding its usefulness in populations with milder forms of cognitive impairment, including subcortical dementia. One can select the version that best fits one’s requirements as well as patients’ needs. Depending on the version chosen, administration takes between 5 and 20 minutes. Equivalent, alternate forms (Blue and Red) of each MMSE-2 version have been developed to decrease the possibility of practice effects that can occur over serial examinations. Items have obvious relationships to functional ability in daily life. Finally, the Pocket Norms Guide has been updated to include norms for all three versions of the MMSE-2 by age and education level and includes reliable change scores to facilitate serial testing with any of the MMSE-2 versions.